PARADIGM-EXTEND

Accumulating long-term evidence for MicroNet^TM-covered stent safety, efficacy, and durability in primary and secondary stroke prevention: 5-year data from the PARADIGM-Extend prospective academic trial

Objective: To evaluate the feasibility and outcome of routine anti-embolic stent system use in unselected, consecutive patients referred for carotid revascularization (all-comers study).

Conclusion: Long-term clinical and duplex ultrasound evidence is consistent with normal healing and sustained safety and stroke prevention efficacy of the MicroNet^TM-covered embolic prevention stent system, which is routinely used, on top of optimized medical therapy, for stroke prevention in symptomatic and increased-stroke-risk asymptomatic subjects with carotid stenosis recommended for revascularization by the NeuroVascular Team.